基本简介

丁奎岭，男，1966年生，研究生学历，博士学位，研究员，博士生导师。1981年9月—1985年7月就读于郑州大学化学系，获理学学士学位；1985年9月—1987年7月，在郑州大学化学系攻读硕士研究生，师从吴养洁院士，获理学硕士学位；1990年在南京大学化学系获博士学位。2013年当选为中国科学院院士。金属有机化学国家重点实验室学术委员会副主任。19主要从事组合不对称催化，新型手性配体的设计、合成及其应用研究，新的手性催化剂负载化方法等方面研究，针对不对称催化反应选择性和效率的核心科学问题，提出并成功实践了手性催化剂设计的新概念和新方法，建立了“组合不对称催化”方法，发展了一系列高效、高选择性手性催化剂并阐明了催化机制；将基础研究与实际应用紧密结合，多项专利成果授权企业使用并实现了产业化。分别获得国家自然科学二等奖和河南省科技进步一等奖、上海市自然科学一等奖等，获6项发明专利。

研究领域： 1. 组合不对称催化 2. 新型手性配体的设计、合成及应用 3. 手性催化剂负载化新方法

出版著作

代表论著：

1. Mingyue Wu, Zhaobin Han, Kaizhi Li, Ji’en Wu, Kuiling Ding*, Yixin Lu*; Cyclohexyl-Fused, Spirobiindane-Derived, Phosphine-Catalyzed, Synthesis of Tricyclic γ-Lactams and Kinetic Resolution of γ？Substituted Allenoates, J. Am. Chem. Soc. 2019, 141, 16362-16373.

2. Yao Ge, Zhaobin Han,* Zheng Wang, Kuiling Ding*; Ir-Catalyzed Double Asymmetric Hydrogenation of 3,6-Dialkylidene-2,5-diketopiperazines for Enantioselective Synthesis of Cyclic Dipeptides, J. Am. Chem. Soc. 2019, 141, 8981-8988.

3. Linli Zhang, Yitian Tang, Zhaobin Han,* Kuiling Ding*; Lutidine-Based Chiral Pincer Manganese Catalysts for Enantioselective Hydrogenation of Ketones, Angew. Chem. Int. Ed. 2019, 58, 4973-4977.

4. Jia Qiu, Shen Gao, Chaopeng Li, Lei Zhang, Zheng Wang*, Xiaoming Wang, Kuiling Ding*; Construction of All-Carbon Chiral Quaternary Centers via Cu(I)-Catalyzed Enantioselective Reductive Hydroxymethylation of 1, 1-Disubstituted Allenes with CO2, Chem. Eur. J. 2019, 25, 13874-13878.

5. Zhiyao Zheng, Yuxi Cao, Dongsheng Zhu, Zheng Wang*, Kuiling Ding*; Development of Chiral Spiro Phosphoramidites for Rhodium-Catalyzed Enantioselective Reactions, Chem. Eur. J. 2019, 25, 9491– 9497.

6. Peihua Guo, Rui Zhang, Xiaoming Wang, Zheng Wang*, Kuiling Ding*; Synthesis of Chiral Tertiary a,a-Difluoromethyl Carbinols by Cu-Catalyzed Asymmetric Propargylation, Chem. Eur. J. 2019, 25, 16425-16434.

7. Yao Ge, Zhaobin Han,* Zheng Wang, Chen-Guo Feng, Qian Zhao, Guo-Qiang Lin, Kuiling Ding*; Ir-SpinPHOX Catalyzed Enantioselective Hydrogenation of 3-Ylidenephthalides, Angew. Chem. Int. Ed. 2018, 57, 13140-13144.

8. Zhiyao Zheng, Yuxi Cao, Qinglei Chong, Zhaobin Han, Jiaming Ding, Chenguang Luo, Zheng Wang, Dongsheng Zhu, Qi-Lin Zhou, Kuiling Ding*; Chiral Cyclohexyl-Fused Spirobiindanes: Practical Synthesis, Ligand Development, and Asymmetric Catalysis, J. Am. Chem. Soc. 2018, 140, 10374-10381.

9. Xinyi Ren, Zhiyao Zheng, Lei Zhang, Zheng Wang, Chungu Xia*, Kuiling Ding*; Rhodium-Complex-Catalyzed Hydroformylation of Olefins with CO2 and Hydrosilane, Angew. Chem. Int. Ed. 2017, 56, 310-313.

10. Xubin Wang, Xiaoming Wang, Zhaobin Han, Zheng Wang*, Kuiling Ding*; Palladium-Catalyzed Asymmetric Allylic Allylation of Racemic Morita–Baylis–Hillman Adducts, Angew. Chem. Int. Ed. 2017, 56, 1116-1119.

11. Jiawang Liu, Zhaobin Han, Xiaoming Wang, Fanye Meng, Zheng Wang, Kuiling Ding*; Palladium-Catalyzed Asymmetric Construction of Vicinal Tertiary and All-Carbon Quaternary Stereocenters by Allylation of β-Ketocarbonyls with Morita-Baylis-Hillman Adducts, Angew. Chem., Int. Ed. 2017, 56, 5050-5054.

12. Jiawang Liu, Ming Nie, Qinghai Zhou, Shen Gao, Wenhao Jiang, Lung Wa Chung, Wenjun Tang*, Kuiling Ding*; Enantioselective palladium-catalyzed diboration of 1,1-disubstituted allenes, Chem. Sci., 2017, 8, 5161-5165.

13. Xubin Wang, Xiaoming Wang, Zhaobin Han, Zheng Wang*, Kuiling Ding*; Palladium-catalyzed asymmetric allylic amination: enantioselective synthesis of chiral α-methylene substituted β-aminophosphonates, Org. Chem. Front. 2016, 4, 271-276.

14. Jiawang Liu, Zhaobin Han, Xiaoming Wang, Zheng Wang, and Kuiling Ding*; Highly Regio- and Enantioselective Alkoxycarbonylative Amination of Terminal Allene Catalyzed by a Spiroketal-Based Diphosphine/Pd(II) Complex, J. Am. Chem. Soc. 2015, 137, 15346-15349.

15. Yang Li, Zheng Wang, Kuiling Ding*; Minimizing Aryloxy Elimination in RhI-Catalyzed Asymmetric Hydrogenation of Aryloxyacrylic Acids using a Mixed-Ligand Strategy, Chem. Eur. J. 2015, 21, 16387-16390.

16. Lei Zhang, Zhaobin Han, Xiaoyu Zhao, Zheng Wang, Kuiling Ding*; Highly Efficient Ruthenium-Catalyzed N-Formylation of Amines with H2 and CO2, Angew. Chem. Int. Ed. 2015, 54, 6186-6189.

任职情况

国际刊物和国际会议兼职:

1. International Advisory Board Member of Eur. J. Org. Chem.(2006 -)

2. International Advisory Board Member of Chem. Commun.(2008 -)

3. Advisory Board Member of International Symposium on Homogeneous Catalysis (ISHC, 2006, 2008, 2010)

4. Editorial Board Member of Catal. Sci. & Tech. (2010-)

5. International Advisory Board Member of Curr. Org. Synth. (2010 -)

学术经历

教育：

1987.09 - 1990.10 南京大学化学系，博士(导师：吴养洁院士)

1985.09 - 1987.07 郑州大学化学系，硕士研究生(导师：吴养洁院士)

1981.09 - 1985.07 郑州大学化学系，学士

工作经历：

1998.12 - 中国科学院上海有机所研究员、博士生导师

2003.08 - 2003.11 日本名古屋大学访问教授

1995.12 - 1998.11 郑州大学化学系教授(其中1997.9-1998.9 日本东京工业大学UNESCO研究员)

1992.11 - 1995.11 郑州大学化学系副教授(其中1993.9-1994.9 日本龙谷大学理工学部博士后)

1990.10 - 1992.10 郑州大学化学系讲师